KinomeXplorer

KinomeXplorer is an integrated framework for modeling kinase-substrate interactions and aid in the design of inhibitor-based follow-up perturbation experiments. An interactive web interface allows investigation of predicted kinase-substrate interactions from human and major eukaryotic model organisms.

NetworKIN is a method for predicting in vivo kinase-substrate relationships, that augments intrinsic specificities of kinases with cellular context for kinases and phosphoproteins. NetPhorest is a non-redundant collection of 222 sequence-based classifiers for linear motifs in phosphorylation-dependent signaling, including kinases, phosphatases, SH3 domains and more.


Additional resource: KinomeSelector which enables the user select an optimal kinase panel to assess the kinome-wide selectivity of kinase inhibitors.

Institutes behind NetworKIN Institutes behind NetworKIN
(C) 2005-2013 Rune Linding and Lars Juhl Jensen
Web-development: Heiko Horn and Jinho Kim

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