KinomeXplorer is an integrated framework for modeling kinase-substrate interactions and aid in the design of inhibitor-based follow-up perturbation experiments. An interactive web interface allows investigation of predicted kinase-substrate interactions from human and major eukaryotic model organisms.
If you use any of the data from this web site please cite this article: Horn et al., KinomeXplorer: an integrated platform for kinome biology studies. Nature Methods 2014 Jun;11(6):603–4.
If you use any of the data from this web site please cite this article: Horn et al., KinomeXplorer: an integrated platform for kinome biology studies. Nature Methods 2014 Jun;11(6):603–4.
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| NetworKIN is a method for predicting in vivo kinase-substrate relationships, that augments intrinsic specificities of kinases with cellular context for kinases and phosphoproteins. | NetPhorest is a non-redundant collection of 222 sequence-based classifiers for linear motifs in phosphorylation-dependent signaling, including kinases, phosphatases, SH3 domains and more. |
Additional resources:
- KinomeSelector which enables the user select an optimal kinase panel to assess the kinome-wide selectivity of kinase inhibitors.
- ReKINect which predicts network-attacking mutations from NGS data
- KINspect where we studied determinants of specificity in the Human kinome
